阿尔茨海默病患者和健康人之间的饮食模式平衡:使用多因素分析和分类建模的综合分析
Tahera Ahmed1, Ping Zhang2, Kuldeep Kumar1
1Centre for Data Analytics, Bond Business School, Bond University, Gold Coast, Australia.
Journal of Alzheimer's disease : JAD
|January 8, 2024
概括
加工食品和肉类繁重的饮食与阿尔茨海默病 (AD) 有关. 饮食平衡可能会影响AD风险,特定的加工食品在受影响的个体中显示出显著的关联.
科学领域:
- 营养科学 营养科学
- 神经科学是一个神经科学.
- 老年学是一门学科.
背景情况:
- 阿尔茨海默病 (AD) 是一种进展性痴呆症,缺乏治愈方法.
- 生活方式,饮食和饮酒习惯可以影响AD风险和严重程度.
研究的目的:
- 为了比较患有阿尔茨海默症的人与健康对照者的日常饮食模式.
- 研究营养平衡对阿尔茨海默病的影响.
主要方法:
- 多因素分析 (MFA) 用于饮食模式评估.
- 随机森林 (RF) 和稀疏物流回归 (SLR) 用于变量重要性分析.
- 标识与AD显著相关的食品.
主要成果:
- MFA显示加工/肉类食品消费与阿尔茨海默病患者之间存在很强的相关性 (Lg=0.92,RV=0.65).
- 在健康对照组中没有发现显著的饮食关系.
- 与阿尔茨海默病相关的关键食物包括肉饼,汉堡,火腿,香肠,牛肉,菜和卷心菜.
结论:
- 饮食的多样性和平衡可能在阿尔茨海默病的发展中起作用.
- 加工食品,特别是熟食食品和肉类产品,与AD有关.
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