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横跨不同双能CT平台的量化的患者内部变异性:对规范化技术的评估

Simon Lennartz^1,2, Jinjin Cao¹, Nisanard Pisuchpen^1,3

¹Department of Radiology, Abdominal Radiology Division, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, White 270, Boston, MA, 02114-2696, USA.

European radiology

|January 8, 2024

概括

患者内度 (IC) 的变化在双能CT (DECT) 平台之间有所不同,正常化减少但不消除扫描仪特异性的影响,特别是在肝脏和胰腺.

科学领域:

放射学放射学是一门学科.
医疗成像医学成像
CT CT 技术技术技术

背景情况:

双能CT (DECT) 平台在度 (IC) 测量中表现出差异.
不同DECT系统之间IC的患者内变异性尚未完全理解.
通过DECT扫描仪对IC量化的标准化对于精确的癌症随访至关重要.

研究的目的:

在三个不同的DECT平台上评估IC的患者内变异性:双源 (dsDECT),快速kVp切换 (rsDECT) 和双层探测器 (dlDECT).
评估不同规范化方法在减少IC变异性的有效性.
为了确定影响IC变异性的因素,包括扫描器类型和对比介质的管理.

主要方法:

在dSDECT,rsDECT和dLDECT平台上对44名癌症随访患者的腹部DECT扫描进行了回顾性分析.
在肝脏,胰腺和脏中的IC的量化,以及正常化的IC (NIC_PV,NIC_AA,NIC_ALL).
纵向混合效应分析,以确定扫描器类型,扫描顺序,间扫描时间和对比度体积对正常化IC的影响.

主要成果:

在DECT扫描仪之间,脏显示的IC变异性最低 (10.9215.76%),而肝脏显示的最高 (22.8529.08%).
对整体负荷 (NIC_ALL) 的正常化最有效地减少了大多数扫描仪间比较和组织中的IC变异性.
尽管正常化,DECT扫描仪类型仍然是影响肝脏和胰腺IC变异性的重要因素 (p < 0.0001).

结论:

在不同类型的DECT扫描仪中存在显著的组织特异性内科IC变异性.
规范化策略可以减轻,但不能完全消除,由于生理波动和扫描器差异的IC变化.
对DECT衍生IC的临床解释需要考虑扫描仪类型和潜在的扫描仪间变异性,特别是在肝脏和胰腺.

关键词:

对比媒介对比媒介.结果的可复制性结果的可复制性断层扫描 (X射线计算) 的使用

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