混合性结石:尿路结石的组成,频率和按性别和年龄的分布
Roswitha Siener1, Jakob Rüdy2, Helena Herwig2
1Department of Urology, University Stone Center, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany. Roswitha.Siener@ukbonn.de.
Urolithiasis
|January 8, 2024
概括
分析尿路结石成分对于尿病管理至关重要. 这项研究发现混合性石头很常见,成分数量随着年龄的增长而下降,而男性更容易发生单元石头.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 材料科学 材料科学 材料科学
背景情况:
- 尿路结石成分分析对于诊断尿病 (结石) 是至关重要的.
- 了解石材成分有助于针对性治疗和预防复发.
- 混合尿路结石会带来诊断和治疗方面的挑战.
研究的目的:
- 为了确定混合尿路结石的组成,频率和分布.
- 根据患者的性别和年龄分析这些因素.
- 为了研究石头复杂性和患者人口统计学之间的关系.
主要方法:
- 分析了来自30,311名男性和12208名女性的42519个尿路结石 (2007-2020年).
- 根据组成部分的数量对石头进行分类 (单,二,三,四).
- 主要石材成分的识别,包括韦韦莱特 (COM),韦德莱特 (COD) 和碳酸酸盐 (CA).
主要成果:
- 大多数石头有两个组成部分 (50.9%),其次是单个 (27.1%) 和三个 (21.9%) 组成部分.
- 惠威莱特/韦德莱特混合物占49.8%;碳酸酸盐混合物占33.8%;尿酸石头占7.6%.
- 石材成分数与年龄相反相关 (p<0.001),女性比例随石材复杂性而增加.
结论:
- 大多数尿路结石是多组件的,具有挑战性的诊断和预防.
- 年龄与石头组成部分的数量相反.
- 性别分布向女性转移,随着石头复杂性的增加.
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