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Updated: Jul 6, 2025

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Published on: June 8, 2019

在直接的术后环境中循环瘤DNA.

Vasileios Efthymiou¹, Natalia Queenan¹, Markus Haas¹

¹Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA, USA.

Annals of surgical oncology

|January 8, 2024

概括

在手术后不久检测循环瘤DNA (ctDNA) 准确预测癌症复发风险. 这种生物标志物显示出在各种固体瘤中引导辅助治疗决策的潜力.

科学领域:

在瘤学瘤学.
分子诊断学分子诊断
癌症生物标志物癌症生物标志物

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Last Updated: Jul 6, 2025

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Published on: June 8, 2019

Detection of Cell-Free DNA in Blood Plasma Samples of Cancer Patients

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Published on: May 14, 2019

背景情况:

循环瘤DNA (ctDNA) 是固体瘤疾病状况的实时生物标志物.
目前的ctDNA实用性研究往往错过了早期辅助治疗决策点.
本综述评估了ctDNA作为直接术后期生物标志物的可行性.

结论:

手术后的ctDNA检测能力预测了癌症类型的复发.
早期的术后ctDNA可以指导最小残留疾病评估.
需要进一步的研究来确定精确的ctDNA动力学和跨瘤类型的最佳时间.