在患有异常REM睡眠行为障碍的患者的眼睛中阅读思想
Xudong Li1,2, Miaoxin Shen3, Zhihong Shen4
1Department of Cognitive Disorder, Beijing Tiantan Hospital, Capital Medical University, Fengtai District, South 4th Ring Road West 119, Beijing, 100070, China. lixd73cj@163.com.
异常性REM睡眠行为障碍 (iRBD) 患者表现出与对照组相似的阅读眼睛中的思想 (RME) 评分. 然而,iRBD中RME受损与认知缺陷相关,特别是在记忆中.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 认知神经科学 认知神经科学
背景情况:
- 异常性REM睡眠行为障碍 (iRBD) 是α-synucleinopathies的一个前兆阶段.
- 通过阅读眼睛中的思想 (RME) 来评估的情感思维理论 (ToM),在α-synucleinopathy中显示出不一致的结果.
研究的目的:
- 在患有异常REM睡眠行为障碍 (iRBD) 的患者中调查阅读眼睛中的思维 (RME) 性能.
- 探索iRBD患者的RME得分和认知功能之间的关系.
主要方法:
- 通过RME和认知测试评估了35名iRBD患者和26名健康对照.
- 根据得分 (≥21或≤20) 将iRBD患者分为高或低RME组.
主要成果:
- 与对照组相比,iRBD患者在全球认知查,记忆和视觉空间测试中表现较差.
- 在iRBD患者和健康对照者之间没有发现RME得分的显著差异.
- 在iRBD患者中,较低的RME得分与更明显的认知障碍相关,特别是在记忆和执行功能方面.
结论:
- 在眼睛中阅读思想 (RME) 的表现与异常REM睡眠行为障碍 (iRBD) 的认知障碍有关.
- 记忆缺陷特别与iRBD患者的改变RME有关.
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