运动训练 独立于强度 降低血胆酸 在糖尿病前期
Steven K Malin, U S Afsheen Syeda1
1Department of Kinesiology and Health, New Brunswick, NJ.
Medicine and science in sports and exercise
|January 8, 2024
概括
在糖尿病前期的老年人中,两周的间隔和连续运动训练降低了胆酸 (BA). 这种降低BA与改善的胰岛素敏感性有关,无论运动强度如何.
科学领域:
- 运动生理学 运动生理学
- 代谢健康 代谢健康
- 内分泌学 在内分泌学.
背景情况:
- 肥胖与循环胆酸 (BA) 的升高有关.
- 有氧健身通常与较低的BA水平相关.
- 在显著减肥之前,运动训练强度对BA的影响仍然不清楚.
研究的目的:
- 为了研究2周间隔 (INT) 与连续 (CONT) 运动对血BA水平的影响.
- 为了确定BA的变化是否与胰岛素敏感性改善有关.
- 测试运动强度影响BA减轻的假设.
主要方法:
- 23名糖尿病前期的老年人接受了为期2周的INT或CONT自行车运动.
- 使用了与工作相匹配的炼方案,其强度和工作间隔不同.
- 口服葡萄糖耐受性测试 (OGTT) 评估了葡萄糖耐受性,胰岛素敏感性和代谢灵活性.
- 禁食和OGTT后的血BA使用液态染色体质谱测量.
- 评估了心肺呼吸能力 (V·O2峰值) 和人体测量.
主要成果:
- INT和CONT运动都降低了体重指数 (BMI) 和改善了胰岛素敏感性.
- 与持续训练相比,间歇训练显著提高了心肺健康 (V·O2峰值).
- 运动导致了几种非结合和结合的BA的显著减少.
- 改善的胰岛素敏感性与较低的特定BA水平相关,特别是甘氨酸 (GCDCA).
- 增加的代谢灵活性与特定的BA变化有关.
结论:
- 短期的运动训练有效地降低了糖尿病前期患者的某些胆酸.
- 降低BA与改善的胰岛素敏感性有关.
- 在研究的参数中,这些有益的BA变化发生在运动训练强度和运动训练强度之间独立.
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