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Updated: Jul 6, 2025

Capillary Electrophoresis Separation of Monoclonal Antibody Isoforms Using a Neutral Capillary
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疏水性相互作用染色体的选择性和分辨力 针对单克隆抗体变体的分离

Raphael Ewonde Ewonde1, Katharina Böttinger2, Jelle De Vos1

  • 1Department of Chemical Engineering, Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050 Brussels, Belgium.

Analytical chemistry
|January 8, 2024
PubMed
概括

针对trastuzumab变种的疏水性相互作用色谱 (HIC) 方法开发是使用化物离子优化,以提高选择性. 这种方法通过了解保留机制,提高了不同形式的trastuzumab之间的分辨率.

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