卡巴胺与非卡巴胺抗生素用于呼吸机相关的肺炎:系统性审查与元分析
Hisayuki Shuto1, Kosaku Komiya2, Kazuya Tone3
1Respiratory Medicine and Infectious Diseases, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita, 879-5593, Japan.
卡巴胺抗生素对呼吸机相关肺炎 (VAP) 没有生存益处. 非碳烯选择可能有助于预防碳烯耐药性病原体,为VAP提供可行的替代治疗方法.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 呼吸机相关肺炎 (VAP) 治疗指南建议使用卡巴.
- 最近关于卡巴尼姆对VAP的疗效的系统审查缺乏.
- 这项研究评估了卡巴胺与非卡巴胺对VAP的疗效.
结论:
- 碳烯可能不会为VAP提供生存优势.
- 针对P. aeruginosa活跃的非碳烯胺抗生素是潜在的替代品.
- 使用非碳烯物质可能有助于防止抗碳烯物质的病原体的出现.
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