转动脉化学栓塞与伦瓦替尼布结合治疗肝细胞癌:随机对照试验的系统审查和元分析
Xiaxia Pei1, Jun Zhao2, Zhiping Wang3
1Department of Oncology, Second Hospital of Lanzhou University, Lanzhou, China, lingyier1220@163.com.
Oncology
|January 8, 2024
概括
通过动脉化学栓塞 (TACE) 与伦瓦提尼布结合,显著改善了肝细胞癌 (HCC) 患者的客观反应率和整体存活率. 这种组合疗法显示出有希望的疗效,尽管它与增加的副作用有关.
科学领域:
- 肝细胞癌研究 肝细胞癌研究
- 在瘤学瘤学.
- 临床试验分析
背景情况:
- 肝细胞癌 (HCC) 治疗往往涉及跨动脉化学栓塞 (TACE) 或单独使用伦瓦替尼.
- 没有随机对照试验 (RCT) 的元分析存在于HCC的TACE和lenvatinib结合方法.
- 这项研究旨在评估TACE和伦瓦提尼布联合治疗HCC的疗效和安全性.
结论:
- 在TACE和lenvatinib的组合显示出对HCC治疗有希望的疗效.
- 这种方法导致延长整体存活率和提高客观反应率.
- 对管理增加的不良影响进行进一步的调查是有必要的.
更多相关视频
09:49Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
Published on: December 2, 2013
10.3K
09:11Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
443
相关概念视频
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Targeted Cancer Therapies
7.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.6K
