在中国老年人中,BMI与认知障碍之间的关系中的性别差异
Journal of affective disorders
|January 8, 2024
概括
老年人的身体质量指数 (BMI) 和认知障碍 (CI) 显示出一个U形的联系. 保持健康的BMI对于大脑健康至关重要,特别是对于男性来说,以减少认知能力下降的风险.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 身体质量指数 (BMI) 和认知障碍 (CI) 之间的关系已被广泛研究,但缺乏精确的剂量反应细节.
- 了解这种关联对于开发针对老年人群认知健康的有针对性的干预措施至关重要.
研究的目的:
- 在一大群老年人中调查身体质量指数 (BMI) 和认知障碍 (CI) 之间的剂量反应关系.
- 探索BMI和CI之间的关系中的潜在性别差异.
主要方法:
- 利用了来自中国长度健康长寿调查 (CLHLS) (2011/2012,2014,2018) 的数据.
- 采用多重后勤回归和限制立方线 (RCS) 模型来分析BMI类别和CI之间的非线性关联.
- 包括29,380名65岁至117岁的参与者.
主要成果:
- 在老年人中,BMI和CI之间确定了U形关系.
- 在女性中,体重不足 (OR:1.32) 和超重 (OR:0.86) 与CI有关,而在男性中没有发现相关性.
- 最低CI风险的最佳BMI为男性约22.8公斤/平方米,女性约24.8公斤/平方米.
结论:
- 老年人BMI和CI之间存在U形关联,在男性和女性的特定BMI范围内观察到的风险最低.
- 这种关系在男性中显得更加明显,这表明在这个人口群体中需要严格的BMI管理来支持认知健康.
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