基于机器学习的放射学来区分肺腺癌和肺结核之间的肺结节
Yuan Li1, Baihan Lyu2, Rong Wang3
1Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Thoracic cancer
|January 8, 2024
概括
放射学有效地区分肺腺癌 (LUAD) 和结核病 (TB) 使用机器学习. 在细分中包含或排除腔区域并没有显著影响这些放射学模型的诊断性能.
科学领域:
- 医疗成像医学成像
- 人工智能在医学中的应用
- 在瘤学瘤学.
背景情况:
- 放射学是一个不断发展的领域,用于区分肺结节,特别是肺腺癌 (LUAD) 和结核病 (TB).
- 关于细分标准的影响存在不确定性,特别是空腔的包含/排除,对放射学性能.
研究的目的:
- 评估基于机器学习的放射学策略的有效性,以区分LUAD和TB.
- 为了确定细分标准 (腔内含与排除) 是否影响放射学模型的预测性能.
主要方法:
- 对来自两个医疗中心的525名患者的回顾性分析.
- 使用两个兴趣区域 (ROI) 分段标准提取放射性特征:包括空洞 (放射性+) 和排除空洞 (放射性-).
- 开发和比较临床,放射学和复合物流回归模型用于病理学预测.
主要成果:
- 放射学和复合模型显示出高预测性能 (AUC ≥0.94在测试中,0.801-0.825在验证中),显著超过临床模型 (AUC 0.881在测试中,0.717在验证中).
- 在包含或排除腔区域的模型之间没有观察到预测性能的显著差异 (p > 0.05).
结论:
- 基于机器学习的放射学策略可以可靠地区分LUAD和结核病病变.
- 在ROI细分过程中包含或排除腔区域不会显著影响放射学模型对这种差异化的预测准确性.
相关概念视频
Pulmonary Tuberculosis IV
143
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
143
Pulmonary Tuberculosis III
332
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
332
Radiological Investigation III: Pulmonary Angiogram and PET Scan
93
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
93
Pulmonary Tuberculosis I
243
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
243
Pulmonary Tuberculosis II
239
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
239


