鼠标模型评估瘤微环境在癌症进展和治疗反应中的功能作用

Kathleen M McAndrews1, Krishnan K Mahadevan2, Raghu Kalluri1,3,4

  • 1Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA rkalluri@mdanderson.org kmmcandrews@mdanderson.org.

概括

了解瘤微环境 (TME) 对癌症治疗至关重要. 基因工程小鼠模型为TME动态如何影响癌症进展和治疗反应提供了关键的见解.