理想的心血管健康指标可以更好地识别关节炎
Yuxiang Wang1, Mengzi Sun1, Nan Yao1
1Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, 1163 Xinmin Avenue, 130021, Changchun, P. R. China.
BMC public health
|January 8, 2024
概括
达到理想的心血管健康指标 (ICVHM) 显著降低了关节炎的风险. 在美国成年人中,较高的ICVHM分数提供了对关节炎 (AR) 和其亚型的保护性益处.
科学领域:
- 心血管健康 心血管健康
- 类风湿病学 类风湿病学
- 公共卫生 公共卫生
背景情况:
- 心血管健康对整体健康至关重要.
- 关节炎 (AR) 包含各种关节疾病,如骨关节炎和类风湿性关节炎.
- 了解心血管健康和关节炎之间的联系对于预防策略至关重要.
研究的目的:
- 研究美国成年人理想心血管健康指标 (ICVHM) 和关节炎 (AR) 之间的关联.
- 探索与AR相关的ICVHM指标之间的相互作用.
- 为关节炎的识别和预防提供见解.
主要方法:
- 分析了来自NHANES (2011-2018) 的17041名参与者.
- 关节炎的分类为骨关节炎,类风湿性关节炎和其他形式.
- 应用物流回归和混合图形模型 (MGM) 来评估关联和相互作用.
主要成果:
- 较高的ICVHM得分表明对AR有显著的保护作用 (ORs在0.586到0.130之间).
- 这种保护性关联在不同类型的关节炎中是一致的.
- ICVHM显示出强大的预测能力 (AUC=0.765),血压和总胆固醇之间有显著的相互作用.
结论:
- 理想的心血管健康指标与减少关节炎患病率有显著的相关性.
- ICVHM是一个比单个指标更有效的关节炎指标.
- 针对具有强烈相互作用的可修改心血管风险因素,可以加强关节炎预防工作.
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