器官捐赠者中的COVID-19:一个器官采购组织的视角
Alyssa K Mezochow1, Judith Anesi1, Sharon West2
1Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
概括
器官采购组织 (OPO) 可以成功地利用对SARS-CoV-2 (导致COVID-19的病毒) 阳性捐赠者进行非肺移植. 这项研究表明,随着时间的推移,这些捐赠者的使用越来越多.
科学领域:
- 移植免疫学 移植免疫学
- 传染病流行病学 传染病流行病学
- 器官采购科学 器官采购科学
背景情况:
- 由于COVID-19的流行,影响了器官采购组织 (OPO) 的实践.
- 在对SARS-CoV-2阳性测试的捐赠者的利用中存在变化.
研究的目的:
- 评估使用SARS-CoV-2阳性捐赠者的成功率.
- 分析这些捐赠者的器官利用率在单个OPO内.
主要方法:
- 对SARS-CoV-2阳性捐赠者的回顾性队列研究.
- 从2021年1月1日到2023年6月30日收集的数据.
- 对捐赠者推和器官利用的描述性分析.
主要成果:
- 在861名SARS-CoV-2阳性转诊者中,有148人成为了捐赠者.
- 在鼻和下呼吸道测试之间发现了显著的不一致.
- 移植的器官包括心脏,肝脏,胰腺和脏;没有移植肺.
- 在研究期间,COVID-19阳性捐赠者的比例增加.
结论:
- 越来越多的COVID-19转介正在向捐赠方面取得进展.
- SARS-CoV-2阳性捐赠者越来越适合用于非肺移植.
- 这支持在器官移植中扩大这些捐赠者的使用范围.
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