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一种通过设计的质量方法,用于开发载有韦穆拉费尼布的SNEDDS,以提高口服生物可用性

Chakradhar Jvus1, Naresh Kothuri1, Sanjay Singh1

  • 1Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, U.P., India.

AAPS PharmSciTech
|January 9, 2024
PubMed
概括

韦穆拉费尼布 (VMF) 是一种难以溶解的药物,使用一种新的自纳米乳化药物输送系统 (SNEDDS) 显著改善了口服生物利用性. 这种配方增强了药物输送和治疗潜力.

关键词:
在SNEDDS中,您可以使用SNEDDS.在 UPLC 中,您可以使用 UPLC生物可用性 生物可用性药物动力学 药物动力学在Vemurafenib中使用.

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