超越潜伏和活跃结核病:概念框架的范围审查
Syed M A Zaidi1,2,3, Anna K Coussens4,5,6, James A Seddon7,8
1WHO Centre for Tuberculosis Research and Innovation, Institute for Global Health, University College London, UK.
EClinicalMedicine
|January 9, 2024
概括
结核病 (TB) 在潜伏或活跃疾病之外的频谱中存在. 这次审查绘制了概念框架,揭示了结核病状态的不一致术语,并突出了对标准化,非二元分类系统的需求.
科学领域:
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 目前的结核病 (TB) 分类是二进制的 (潜伏与活跃).
- 对一系列结核病感染和疾病状况的认识越来越多.
- 需要一个更细微的理解超越二进制模型.
研究的目的:
- 为结核病国家系统地绘制和综合出版的概念框架.
- 识别和分类用于描述结核病状态的不同概念主题.
- 突出术语,定义和诊断标准中的不一致性.
主要方法:
- 在MEDLINE,Embase和EMcare系统搜索评论文章.
- 包括40篇文章,明确描述了两个以上的结核病状态.
- 对已识别的概念主题及其普遍性的分析.
主要成果:
- 为结核病国家确定了八个广泛的概念主题 (国家0-VII).
- 国家范围从消除mtb到严重传播结核病.
- 在研究中,术语,定义和诊断标准存在重大不一致.
结论:
- 需要就结核病国家非二元框架达成共识.
- 标准化对于科学传播至关重要.
- 告知结核病研究,临床实践和公共卫生方面的进展是必不可少的.
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