昼夜节律与良性前列腺激增症 (BPH) /下泌尿道症状 (LUTS) 之间的联系
Dana Cavanaugh1,2, Alfonso Urbanucci3,4, Nihal E Mohamed1,2
1Department of Urology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
The Prostate
|January 9, 2024
概括
循环节律障碍可能会影响良性前列腺激增症 (BPH) 和下泌尿道症状 (LUTS). 需要更多的研究来了解这种联系及其对BPH治疗结果的影响.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 时间生物学 时间生物学
- 男人的健康 男人的健康
背景情况:
- 良性前列腺增生症 (BPH) 是老年男性常见的疾病,严重影响生活质量.
- 导致BPH和下泌尿道症状 (LUTS) 的潜在因素包括衰老,炎症,代谢综合征和荷尔蒙变化.
- 假设循环节律扰乱间接影响这些与BPH相关的过程.
研究的目的:
- 审查目前关于昼夜节律扰乱和BPH发病之间的关联的证据.
- 探索昼夜节律扰乱对BPH治疗的影响.
主要方法:
- 进行了叙事文学评论.
- 在PubMed和谷歌学者进行了搜索.
- 包括在1975年至2023年间发表的文章.
主要成果:
- 目前尚未确定BPH/LUTS与昼夜节律障碍之间的确切联系.
- 诸如炎症,代谢综合征和荷尔蒙调节等常见因素连接了这两种情况,并受到昼夜干扰的影响.
- 虽然一些研究表明LUTS和睡眠障碍之间存在联系,但对治疗结果的研究有限.
结论:
- 有证据表明BPH/LUTS和昼夜节律障碍之间存在潜在的关系.
- 缺乏专门讨论昼夜节律扰乱对BPH医疗管理和治疗结果的影响的文献.
- 需要进一步的研究来指导BPH患者的昼夜节律干预措施.
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