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Updated: Jul 6, 2025

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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埃尔夫1促进Rad26与受伤停止的Pol II的相互作用,用于转录合修复

Reta D Sarsam1, Jun Xu2, Indrajit Lahiri1

  • 1Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093.

Proceedings of the National Academy of Sciences of the United States of America
|January 9, 2024
PubMed
概括

考凯恩综合征B蛋白 (CSB) 和ELOF1是DNA修复的关键. 新结构揭示了CSB和Elf1如何合作在转录合核酸切割修复 (TC-NER) 过程中识别DNA损伤.

关键词:
卡卡恩综合征 B 类型十一 一个的RNA聚合酶II.低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.转录合修复的修复方法

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