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Updated: Jul 6, 2025

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一种SOX4的修饰通过YTHDF3的识别来调节骨质细胞的增殖和分化

Zhi-Wei Feng1, Bo Peng2, Sheng-Hong Wang2

  • 1Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, China; Gansu Province Orthopaedic Clinical Medicine Research Center, Lanzhou, China; Gansu Province Intelligent Orthopedics Industry Technology Center, Lanzhou, China; Department of Orthopaedics, Nanchong Central Hospital, The Second Clinical Institute of North Sichuan Medical College, Nanchong, China.

Cellular signalling
|January 9, 2024
PubMed
概括

甲基转移酶Like-3 (METTL3) 通过修改SOX4mRNA来调节骨的形成. 这种METTL3-m6A-SOX4-YTHDF3通路对骨质细胞功能至关重要,可能是骨质疏松症的治疗点.

关键词:
M(6) 一个修改修改.在METTL3中,METTL3是METTL3的第一个类型.骨质疏松症是一种骨质疏松症.这就是SOX4的SOX4.这就是YTHDF3的原因.

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