操纵与海草相关的微生物组可以减少疾病的严重程度
Olivia J Graham1, Emily M Adamczyk2, Siobhan Schenk3
1Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, New York, USA.
Environmental microbiology
|January 9, 2024
概括
鱼叶微生物组不会防止衰老疾病. 微生物组的实验性减少导致了更高的疾病严重程度,挑战了以前关于海洋植物微生物相互作用的假设.
科学领域:
- 海洋生物学 海洋生物学
- 微生物学 微生物学
- 植物病理学 植物病理学
背景情况:
- 与宿主相关的微生物对健康和抗病能力至关重要.
- 陆地植物微生物组赋予各种病原体的耐药性.
- 海洋植物微生物组在疾病耐药性中的作用仍未得到充分研究.
研究的目的:
- 调查鱼草 (Zostera marina) 叶微生物组在抵抗海草消耗病中的作用.
- 为了测试鱼草微生物组增强抗病能力的假设.
主要方法:
- 现场抽取患病和无症状鱼草的样本.
- 16S rRNA基因扩增序列测序用于分析细菌群落.
- 使用抗生素和漂白剂对鱼草微生物组进行实验性操纵.
- 用 Labyrinthula zosterae 进行注射,这是一种消耗性疾病的病原体.
主要成果:
- 细菌的组成和丰富性在两年中的一个病变和无症状组织之间有所不同.
- 环境条件可能会影响疾病对微生物群落的影响.
- 实验性微生物组减少导致明显更高的衰竭疾病严重程度.
- 鱼草微生物组没有显示出对Labyrinthula zosterae的保护作用.
结论:
- 鱼草微生物组似乎没有对海草消耗病产生抵抗力.
- 海洋宿主-微生物-病原体相互作用可能是复杂的,并且取决于环境.
- 需要进一步的研究来阐明海洋植物微生物组在疾病动态中的功能.
更多相关视频
08:14A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model
Published on: February 28, 2018
8.8K
09:49Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
Published on: October 31, 2019
22.4K
相关概念视频
Gene Regulation in Microbial Communities: Quorum Sensing
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
Microbe-Plant Interactions
Microbe-plant interactions represent a dynamic spectrum of associations shaped by intricate chemical signaling. These interactions can be neutral, beneficial, or detrimental, and profoundly influence plant physiology, growth, and ecosystem function. The plant microbiome, comprising bacteria, fungi, archaea, protists, and viruses, plays a pivotal role in mediating these effects through surface colonization, internal colonization, or systemic symbiosis.Mutualistic associations, particularly with...
Marine Microbial Ecology
Marine microbial ecosystems are shaped by distinct physicochemical limits, including high salinity, low nutrient availability, and fluctuating oxygen levels. These conditions favor smaller microbial cell sizes, which maximize their surface-to-volume ratio for efficient nutrient uptake.Microbial activity and community composition are closely linked to biogeochemical cycles, particularly in dynamic environments like estuaries, where halotolerant microbes thrive in response to variable salinity...
Dysbiosis of the Gut Microbiota
The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibrium—referred to as dysbiosis—can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...
Gut-Brain Axis
The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...
Microbiota Modulation by Antibiotics
Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...
