技术和对ASSIST全球注册表初级结果的第一通效应的影响
Rishi Gupta1, Salvador Miralbés2, Angel Calleja Bonilla2
1Neurosurgery, WellStar Health System, Marietta, Georgia, USA guptar31@gmail.com.
Journal of neurointerventional surgery
|January 9, 2024
概括
在急性缺血性中风的机械血栓切除术中,支架取回技术 (SR经典和SR组合) 对于第一通复注更有效. 临床结果和安全性在所有技术中都是相似的.
科学领域:
- 神经学 神经学
- 干预性神经放射学 干预性神经放射学
- 心血管疾病 心血管疾病
背景情况:
- 机械血栓切除术 (MT) 通过有效的再注射改善了来自大血管封闭 (LVO) 的急性缺血性中风 (AIS) 的结果.
- 实现成功的第一通再输的最佳MT技术仍然不清楚.
研究的目的:
- 为了比较不同的MT技术在成功实现第一通透再输的有效性.
- 评估MT技术对临床结果和安全的影响.
主要方法:
- 未来的,多中心的全球注册表,包括1492名为LVO接受MT的患者.
- 评估了三种技术:支架检索器经典 (SR经典),支架检索器组合 (SR组合) 和直接吸收 (DA).
- 主要结局:第一通再输 (eTICI 2c或3);次要结局:90天的mRS 0-2.
主要成果:
- 与DA (P=0.01) 相比,SR经典和SR组合技术与更高的第一通再输率 (eTICI 2c或3) 有关.
- 在90天的功能性结果 (mRS 0-2) 或安全性终点方面,在两种技术之间没有发现显著差异.
结论:
- 在AIS的MT期间,SR经典和SR组合在实现第一通的再注射方面取得了卓越的技术成功.
- 在这个队列中,选择MT技术并没有显著影响临床结果或安全性.
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