在临床嗅觉任务上最大喉角的变化在与健康对照组相比,在有功能性和有机性喉病理的患者中有所不同
Brett Welch1, Katherine Gold2, Jackie Gartner-Schmidt3
1University of Pittsburgh, Pittsburgh, Pennsylvania.
Journal of voice : official journal of the Voice Foundation
|January 9, 2024
概括
患有喉 dystonia/基本震 (LD/ET) 和矛盾声运动障碍 (PVFMD) 的患者在声运动评估期间表达最大角的更大变化. 这一发现表明,在这些语音和呼吸障碍中,运动一致性可能存在问题.
科学领域:
- 喉腔病理学 喉腔病理学
- 声音科学 声音科学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 灵活的内镜可视化声在"嗅-ee"机动期间对于评估声的移动性至关重要.
- 人类眼睛在精确测量最大眼角的细微差异方面存在局限性.
研究的目的:
- 在患有各种语音和喉呼吸障碍的患者中,在"嗅-ee"动作期间比较最大喉角变量.
- 评估喉角测量是否可以区分健康对照组和特定患者组.
主要方法:
- 灵活喉镜检查的回顾性分析分为六组:喉 dystonia/基本震 (LD/ET),声病变,声缩,矛盾声运动障碍 (PVFMD),肌肉张力失声 (MTD) 和健康对照.
- 在三次"sniff-ee"动作中计算最大口角 (GAMAX) 和平均口角 (GAAVG).
- 用简单的线性回归来比较疾病组和更广泛的疾病类型 (功能性,有机性) 与健康对照.
主要成果:
- 在对照组和任何障碍子组或更广泛的类型 (功能/有机) 之间,没有发现GAMAX或GAAVG的显著差异.
- 与健康对照组相比,在PVFMD (变化6.2°) 和LD/ET (变化5.8°) 中观察到GAMAX变异性的统计学显著差异 (P<0.001).
结论:
- 与健康个体相比,患有LD/ET和PVFMD的患者在GAMAX中表现出明显更大的变化.
- 这种增加的变异性表明,LD/ET和PVFMD患者群体的运动一致性或协调受损.
- 需要进行进一步的研究,以评估LD和PVFMD的眼球角变异的诊断灵敏度和特异性.
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