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相关概念视频

Assessment of the Mouth01:26

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Microbial Morphologies01:29

Microbial Morphologies

Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...
Methods to Assess Microbial Populations01:30

Methods to Assess Microbial Populations

Assessing microbial populations is crucial for understanding microbial roles in health, ecology, and industry. Various complementary techniques—both culture-based and molecular—enable detailed analysis of microbial abundance, diversity, and function.Viable Plate CountThe viable plate count is a traditional culture-based method used to estimate the number of living microbes in a sample. After serial dilution, the sample is spread onto nutrient agar plates. Each viable cell forms a visible...
Methods to Assess Microbial Communities01:19

Methods to Assess Microbial Communities

Microbial communities, comprising bacteria, archaea, and eukaryotic microorganisms, inhabit diverse ecosystems and play crucial roles in environmental and biological processes. Their diversity is defined by three main parameters: species richness (the number of distinct species), species abundance (the relative quantity of each species), and species evenness (how uniformly individual species are distributed in various locations). These factors together shape the structure and ecological balance...
The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...

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相关实验视频

Updated: Jul 5, 2026

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
09:44

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy

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用于破译口腔微生态学的Omics.

Yongwang Lin1, Xiaoyue Liang1, Zhengyi Li1

  • 1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

International journal of oral science
|January 9, 2024
PubMed
概括
此摘要是机器生成的。

技术进步正在彻底改变口腔微生物组研究,使微生物群落的详细分析能够改善口腔和全身健康. 未来的整合有望改变疾病的预测和治疗.

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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
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Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
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科学领域:

  • 微生物学 微生物学
  • 基因组学就是基因组学.
  • 生物技术是生物技术.

背景情况:

  • 人口微生物组是一个复杂而多样化的社区,对口腔和全身健康至关重要.
  • 技术进步正在提高我们研究和操纵口腔微生物群的能力.

研究的目的:

  • 审查口腔微生物组表征和操纵的最新技术创新.
  • 突出综合技术的潜力,以了解口腔健康和疾病.

主要方法:

  • 高通量测序用于分类学和功能分析.
  • 长读测序用于改进基因组组装.
  • 单细胞基因组学用于未培养的种群.
  • 先进的成像 (光学,质谱学,拉曼光谱) 用于空间和代谢洞察.
  • 用于隔离新型口腔种群的文化学.

主要成果:

  • 这些技术提供微生物组织和相互作用的高分辨率可视化.
  • 它们提供了对新陈代谢活动,生物分子指纹和未培养微生物的见解.
  • 整合有望改变对微生物组组装,基因表达和微生物与宿主相互作用的理解.

结论:

  • 关于口腔微生物组的起源,发展和治疗操纵,仍然存在重大知识差距.
  • 测序,成像,文化学和合成模型的融合将推动口腔微生物组研究.
  • 这种融合为预测,预防,诊断和治疗口腔疾病提供了机会.