在患有乳头甲状腺癌的患者中,年龄和远程转移之间的U形关联
Hui Huang1, Song Ni1, Wensheng Liu1
1Department of Head and Neck Surgical Oncology, National Cancer Centre/National Clinical Research Centre for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, China.
Endocrine
|January 10, 2024
概括
被诊断为患有远程转移的乳头甲状腺癌患者表现出与年龄的U形关联. 年轻 (≤21岁) 和老年 (>55岁) 个体的转移发病率高于中年人群.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 乳头甲状腺癌 (PTC) 是最常见的甲状腺癌类型.
- 远程转移是影响PTC预后的关键因素.
研究的目的:
- 调查年龄分布与在乳头甲状腺癌患者中同步远程转移的发生之间的关系.
主要方法:
- 在2013年1月至2018年12月期间接受治疗的PTC患者的回顾性评估.
- 使用受限立方线 (RCS) 的逻辑回归来分析诊断时的年龄和远程转移的关联.
主要成果:
- 在PTC中,年龄和远程转移之间发现了一个U形的关联.
- 与22-55岁患者相比,≤21岁 (OR 2.33) 和>55岁 (OR 3.32) 的患者表现出明显更高的远程转移率.
- 在总患者队列的0.7%中观察到远程转移.
结论:
- 诊断时的年龄显示出U形的关联与皮肤状甲状腺癌的同步远程转移.
- 无论是年轻人还是老年人,在PTC中都存在远程转移的风险.
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