牙周炎和高血压通过全身炎症联系在一起:一项为期5年的纵向研究
Kitti Torrungruang1, Prin Vathesatogkit2, Rangsini Mahanonda3
1Department of Microbiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Journal of clinical periodontology
|January 10, 2024
概括
牙周炎和口腔卫生不良会增加高血压风险. 通过白细胞计数和C反应蛋白来衡量系统性炎症,部分介导了这种联系,突出了口腔健康问题.
科学领域:
- 口腔健康和心血管疾病研究研究
- 炎症和慢性疾病流行病学
背景情况:
- 牙周炎是一种严重的牙感染,越来越多地与全身健康问题有关.
- 高血压是心血管疾病的主要危险因素.
- 系统性炎症在连接牙周炎和高血压中的作用需要进一步阐明.
研究的目的:
- 调查牙周炎和高血压之间的关联.
- 检查系统性炎症在这种关系中的调解作用.
- 为了分析5年纵向研究的数据.
主要方法:
- 使用探测深度 (PD) 和斑块得分评估牙周炎的严重程度.
- 使用回归模型分析了牙周变量与5年血压变化或事件高血压之间的关联.
- 使用白细胞计数 (WBC) 和C反应蛋白 (CRP) 水平进行调解分析.
主要成果:
- 较大的PD和口腔卫生不良与静脉压升高和高血压风险增加相关.
- 牙周炎和口腔卫生不良与较高的白血球和CRP水平有关.
- WBC和CRP联合介导了牙周变量与发生性高血压之间的关联的14.1%-26.9%.
结论:
- 牙周炎和口腔卫生不良与患高血压的风险更高有关.
- 系统性炎症,由WBC和CRP表示,部分介于口腔健康不良和高血压之间的联系.
- 保持口腔卫生可能对心血管健康很重要.
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