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Updated: Jul 6, 2025

Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues
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Published on: June 3, 2016

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Cfp1通过修改结构性,代谢性和收缩性相关基因的希斯H3K4me3来控制心肌细胞成熟

Changzhu Li1, Yang Zhang1, Jingling Shen2

  • 1Department of Pharmacology (State Key Laboratory of Frigid Zone Cardiovascular Disease, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, Heilongjiang, 150086, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|January 10, 2024
PubMed
概括

CXXC指蛋白1 (Cfp1) 对于心肌细胞成熟至关重要. 其缺乏会损害心脏发育,导致心脏病,而其过度表达通过调节质子修饰来促进成熟.

关键词:
在Cfp1中使用.H3K4me3是什么意思 H3K4me3是什么意思心肌细胞成熟的过程这就是hiPSC-CMs.

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