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在复杂的伤口中使用原-弹性质矩阵与分厚皮肤移植来覆盖缺陷

Seyed Arash Alawi¹, Feras Taqatqeh¹, Jan Matschke²

¹Department of Plastic and Hand Surgery, University Center of Orthopedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Germany.

Journal of wound care

|January 10, 2024

概括

原-弹性质矩阵 (CEM) 与分厚皮肤移植 (STSG) 为复杂的伤口重建提供了可行的替代方案. 一步式和两步式方法在实现缺陷关闭方面表现出相似的成功率,特别是在不适合进行手术的患者中.

科学领域:

整形外科手术整形外科手术
再生医学是一种再生医学.
伤口愈合研究研究研究

背景情况:

严重的软组织损伤需要进行塑性重建手术.
多病症患者或那些不适合进行重大手术的患者需要替代治疗方法.
皮肤替代品,如原-弹性基质 (CEM) 与分厚皮肤移植 (STSG) 提供了对手术的替代方案.

研究的目的:

为了比较CEM加STSG的结果,使用一步式与两步式方法.
评估复杂伤口中缺陷重建的成功率.
评估CEM加STSG的可行性,对于不适合皮手术的患者.

主要方法:

追溯后续研究,对46名患者进行了追溯后续研究,其中49名患者的伤口部位接受了CEM和STSG的治疗.
对38名不需要片覆盖的患者进行分析,比较一步骤 (同时进行CEM和STSG) 与两步骤 (CEM与负伤压治疗,然后STSG) 的方法.
平均随访时间为22个月.

主要成果:

总体而言,78.4%的伤口保持关闭.
一步式方法在76.5%的伤口中实现了长期缺陷覆盖,而两步式方法在80.0%中取得了成功.
没有观察到一步和两步方法之间的治疗障碍在统计学上有显著差异.

结论:

在大多数情况下,CEM加STSG有效地治疗了38个复杂的伤口,避免了二次覆盖.
一步式和两步式方法在无式伤口关闭方面表现出相似的有效性.
使用CEM加STSG的简单缺陷重建算法是复杂伤口的成功治疗方法.

关键词:

原-弹性质矩阵复杂的伤口复杂的伤口负压伤口治疗疗法负压伤口治疗软组织覆盖范围软组织覆盖范围分厚的皮肤移植.伤口的伤口是伤口.伤口护理伤口护理伤口上使用了伤口带.伤口愈合伤口愈合伤口治疗疗法伤口治疗

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