富含的水对空心菌的作用
Zhibin Liu1, Eungyung Kim2, Su-Hyung Hong3
1Department of Dental Hygiene, Graduate School of Science and Technology, Kyungpook National University, Sangju-City; Department of Animal Science and Biotechnology, Kyungpook National University, Sangju-City, Gyeongsangbuk, Republic of Korea.
电解富含的水 (EHW) 有效地抑制 cariogenic 细菌的生长和生物膜的形成. 这项研究表明,EHW是一种有前途的中性pH口水,用于口腔卫生.
科学领域:
- 口腔微生物学 口腔微生物学
- 生物技术是生物技术.
- 预防性牙科 预防性牙科
背景情况:
- 电解水表现出抗氧化和杀菌性质.
- 有限的研究存在于中性pH电解丰富水 (EHW) 对抗菌的细菌.
研究的目的:
- 为了评估EHW作为口水的潜力.
- 调查EHW对菌细菌生长和生物膜形成的影响.
主要方法:
- 评估了EHW对Streptococcus mutans和Streptococcus sobrinus的杀菌和抗生物膜作用.
- 测量了细菌生长曲线,殖民地形成单位 (CFU) 和生物膜形成.
- 通过实时PCR评估葡萄糖转移酶和葡萄糖结合蛋白的基因表达.
主要成果:
- 与自来水相比,EHW显著抑制了细菌生长,并减少了CFU.
- EHW显著减少了生物膜的形成.
- EHW降低了参与毒性关键基因 (gtfB, gtfC, gtfI, gbpC, dblB) 的表达.
结论:
- 中性pH EHW在体外有效地抑制 cariogenic 细菌的生长和生物膜的形成.
- EHW显示出作为一种改善口腔卫生的新型口水的潜力.
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