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Updated: Jul 6, 2025

Evaluation of LC3-II Release via Extracellular Vesicles in Relation to the Accumulation of Intracellular LC3-positive Vesicles
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Evaluation of LC3-II Release via Extracellular Vesicles in Relation to the Accumulation of Intracellular LC3-positive Vesicles

Published on: October 18, 2024

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IκB激酶酸化细胞质TDP-43并促进其蛋白质体降解

Yohei Iguchi1, Yuhei Takahashi1, Jiayi Li1

  • 1Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

The Journal of cell biology
|January 10, 2024
PubMed
概括

IκB激酶 (IKK) 复合体降解细胞质TDP-43,这是一种涉及ALS和FTLD的蛋白质. 向IKK和TDP-43酸化可能为这些神经退行性疾病提供新的治疗策略.

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