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Updated: Jul 6, 2025

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension
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特定于内皮的SIRT7向通过克鲁普尔样因子4脱乙烯化来改善肺高血压

Jin Zhang1,2, Chenzhong Xu1,2, Xiaolong Tang2

  • 1Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Marshall Laboratory of Biomedical Engineering, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen 518060, China.

Cardiovascular research
|January 10, 2024
PubMed
概括

赛尔图因7 (SIRT7) 缺乏会损害肺动脉内皮细胞 (PAEC) 在肺高血压 (PH) 中的功能. 通过向SIRT7/KLF4轴恢复SIRT7水平,为PH提供了一个潜在的治疗策略.

关键词:
在KLF4KLF4在SIRT7中使用SIRT7.内皮细胞是内皮细胞.肺高血压是一种肺高血压.

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