通过内部模拟感官刺激和行为行为来保持时间和节奏
Victor de Lafuente1, Mehrdad Jazayeri2, Hugo Merchant1
1Institute of Neurobiology, National Autonomous University of Mexico, Boulevard Juriquilla 3001, Querétaro, QRO 76230, México.
Science advances
|January 10, 2024
概括
大脑在多个区域中使用广泛的神经活动来维持内部节奏,就像一个灵活的计时器一样,在没有外部线索的情况下定时行动.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 计算神经科学是一种神经科学.
背景情况:
- 有效的行为需要与环境变化同步行动.
- 可预测的节奏性环境变化促进了行动的时间.
- 编码和维护内部节律的神经机制在很大程度上是未知的.
研究的目的:
- 研究大脑如何编码和维护内部节律.
- 识别与节律维持有关的大脑区域和神经动力学.
- 探索内部计量器在编码不同节奏时的灵活性.
主要方法:
- 灵长类动物被训练在各种节奏中保持内部节奏.
- 大规模的神经活动记录在感官运动层次上进行.
- 分析的重点是火速和当地场潜在功率的振荡.
主要成果:
- 节奏维护涉及多个大脑区域:视觉,额头,前运动,前额头和海马区域.
- 这些区域的神经活动表现出反射内部计量器的振荡.
- 这种内部计量器灵活地编码了快速,中速和慢速的节奏.
- 即使没有外部刺激或运动动作,也观察到广泛的计量器相关活动.
结论:
- 刺激和行动的内部模拟是计时和节奏维护的基础.
- 大脑利用分布式网络来产生和维持内部节奏.
- 神经振荡在节奏的灵活时间编码中起着至关重要的作用.
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