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Updated: Jul 6, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

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使用GENEHUNTER-MODSCORE的关节链接和关联分析,适用于家族胰腺癌

Markus Brugger1,2,3, Manuel Lutz1,2,3, Martina Müller-Nurasyid1,2,3

  • 1Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.

Human heredity
|January 10, 2024
PubMed
概括

这项研究引入了一种新的基于单元型的关节链接和关联 (JLA) 分析方法,以提高疾病基因映射能力. JLA-MOD得分提高了基因发现,特别是在单个方法不足的复杂疾病中.

关键词:
协会分析 协会分析在家族性胰腺癌.哈普洛型的频率估计估计.链接分析 链接分析在MOD得分上,MOD得分高.

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