在食道癌治愈治疗后进行结构化监测的内镜超声波
Wolfram Bohle1, Lioba Nowack2, Andre Schaudt3
1Department of Gastroenterology, Katharinenhospital, Klinikum Stuttgart, Stuttgart, Germany.
概括
对食道癌的结构化监测有助于早期发现无症状复发. 内镜超声波对于识别局部区域性复发至关重要,使潜在的治愈治疗和改善生存率成为可能.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 医疗成像医学成像
背景情况:
- 缺少已建立的食道癌治疗后监测协议.
- 目前的数据不足以指导后续策略,人们担心密集监测对生存的好处.
- 缺乏标准化的监测,阻碍了食道癌症治疗后的最佳患者管理.
研究的目的:
- 评估结构化监测计划在食道癌治疗后检测瘤复发的有效性.
- 评估特定诊断方法,特别是内镜超声波在确定复发中的作用.
- 确定早期复发检测对治疗结果和存活率的影响.
主要方法:
- 在42名食道癌患者的多式疗法后实施了结构化监测协议.
- 该方案包括定期隔间进行胃镜检查,内镜超声波检查,胸部X射线检查,腹部超声波检查和CEA测量,长达五年.
- 分析包括复发率,复发时间,复发局部,诊断方法,治疗和结果.
主要成果:
- 在42名患者中,有18人经历了瘤复发,其中16人通过结构化监测被诊断为无症状.
- 复发的中位时间为9个月;局部区域复发仅通过内镜超声波检测.
- 六名患有孤立的局部区域复发的患者接受了治愈疗法,实现了长期生存.
结论:
- 结构化监测有效地识别了食道癌症患者的有限和无症状瘤复发.
- 通过内镜超声波早期检测局部复发可以导致长期的生存或治愈.
- 内镜超声波应该是治疗食道癌症治疗后结构化监测的关键组成部分.
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