Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Eukaryotic Compartmentalization01:37

Eukaryotic Compartmentalization

11.0K
One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
For example, lysosomes in the animal...
11.0K
Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

2.5K
Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
2.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Coupling Polyolefin Conversion and Methanol Reduction for C<sub>9</sub>-C<sub>10</sub> Alkylaromatic Production.

Angewandte Chemie (International ed. in English)·2026
Same author

MRI-based breast texture intelligent analysis assists in the diagnosis of BI-RADS category 4 lesions.

European journal of radiology·2026
Same author

Multimodal MRI-based quantification of tumoral spatial heterogeneity for preoperative upgrade prediction of ductal carcinoma in situ.

Scientific reports·2026
Same author

Differential bioenergetic reprogramming driven by sorafenib reveals therapeutic vulnerabilities in biliary tract cancers.

Cancer letters·2026
Same author

Wearable ultrasound: a review of core technologies and clinical applications in cardiovascular monitoring.

Microsystems & nanoengineering·2026
Same author

Effects of physical therapy modalities for early postoperative pain following total knee arthroplasty: a systematic review and network meta-analysis.

Frontiers in rehabilitation sciences·2026

相关实验视频

Updated: Jul 6, 2025

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
06:24

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Published on: December 15, 2017

10.1K

用于微生物代谢工程的设计者蛋白质容器.

Zhen Fang1, Ya-Jiao Zhu1, Zhi-Gang Qian1

  • 1State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, People's Republic of China.

Current opinion in biotechnology
|January 10, 2024
PubMed
概括

合成蛋白质隔间组织细胞代谢,以提高效率和特异性. 这些设计室为代谢重编程提供了多功能工具包,解决了途径控制的关键挑战.

科学领域:

  • 生物化学和合成生物学
  • 细胞和分子生物学是细胞和分子生物学.

背景情况:

  • 蛋白体对细胞代谢至关重要,通过自我组装或相分离来控制反应.
  • 了解它们的结构,形成和功能是细胞过程调节的关键.

研究的目的:

  • 审查合成蛋白质对代谢途径组织的设计和构造.
  • 突出提高代谢效率,降低毒性和管理竞争性途径的战略.

主要方法:

  • 关于合成蛋白质隔间设计和建造的文献综述.
  • 对代谢工程的分隔策略的分析.

主要成果:

  • 合成隔间可以空间组织代谢途径,增加反应速度和特异性.
  • 分体化有效减少有毒中间体的积累,并允许在代谢途径之间切换.

结论:

  • 设计者蛋白质隔间代表了代谢重编程的强大工具包.
  • 需要进一步的研究来克服在代谢工程中广泛应用的挑战.

更多相关视频

Directed Protein Packaging within Outer Membrane Vesicles from Escherichia coli: Design, Production and Purification
10:21

Directed Protein Packaging within Outer Membrane Vesicles from Escherichia coli: Design, Production and Purification

Published on: November 16, 2016

13.4K
Light-Controlled Fermentations for Microbial Chemical and Protein Production
08:37

Light-Controlled Fermentations for Microbial Chemical and Protein Production

Published on: March 22, 2022

4.1K

相关实验视频

Last Updated: Jul 6, 2025

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
06:24

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Published on: December 15, 2017

10.1K
Directed Protein Packaging within Outer Membrane Vesicles from Escherichia coli: Design, Production and Purification
10:21

Directed Protein Packaging within Outer Membrane Vesicles from Escherichia coli: Design, Production and Purification

Published on: November 16, 2016

13.4K
Light-Controlled Fermentations for Microbial Chemical and Protein Production
08:37

Light-Controlled Fermentations for Microbial Chemical and Protein Production

Published on: March 22, 2022

4.1K