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Updated: Jul 6, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
07:09

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CRIP1涉及多发性骨髓瘤的发病因子,通过蛋白质酶和自的双重调节

Peixia Tang1, Zhen Yu1, Hao Sun2

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China; Tianjin Institutes of Health Science, Tianjin, China.

EBioMedicine
|January 10, 2024
PubMed
概括

高CRIP1表达表明多发性骨髓瘤 (MM) 的结果不佳. 这项研究揭示了CRIP1通过调节蛋白酶体和自途径对蛋白酶体抑制剂耐药性的作用,为MM提供了新的治疗见解.

关键词:
自自是一种自的过程.在CRIP1中,我们可以使用CRIP1.多发性骨髓瘤是一种多发性骨髓瘤.在PIs的阻力方面,PIs的阻力蛋白质酶体降解的降解

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