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作为血管新生素AT2受体连接体的N-(Heteroaryl) thiophene硫胺

Johan Wannberg1, Johan Gising2, Martin Henriksson3

  • 1Department of Medicinal Chemistry, Science for Life Laboratory, BMC, Uppsala University, Box 574, SE-751 23, Uppsala, Sweden.

European journal of medicinal chemistry
|January 10, 2024
PubMed
概括

研究人员合成了新型N-(heteroaryl) thiophene硫胺,发现了强大的 ангиотензинII类型2受体 (AT2R) 配体. 最有前途的化合物显示出显著的血管松作用,表明治疗潜力.

关键词:
在AT((2) R连接体中,ангиотензин II 型 2 型受体碳素酸生物异构剂 碳素酸生物异构剂N-甲基硫胺胺基 N-甲基硫胺基

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