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Updated: Jun 14, 2026

Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein
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在临床Pseudomonas aeruginosa分离物中mexB,mexY和oprD表达的变化

Yoshimi Matsumoto1, Seiji Yamasaki1,2,3, Kouhei Hayama1

  • 1SANKEN (The Institute of Scientific and Industrial Research), Osaka University.

Proceedings of the Japan Academy. Series B, Physical and biological sciences
|January 10, 2024
PubMed
概括

排泄抑制剂与诸如西普罗素或阿兹特雷诺南之类的抗生素相结合,在治疗多药耐药性Pseudomonas aeruginosa (MDRP) 感染方面表现有前途. 这种方法针对mexY和oprD等关键基因,增强药物易感性.

关键词:
菲-阿尔格-β-纳菲利胺胺.氨基糖化物乙烯基转移酶的氨基糖化物金属β-乳酸酶的使用.多种药物排放多种药物排放多种药物耐药性多种药物耐药性

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