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Updated: Jul 6, 2025

In Vitro and In Vivo Approaches to Determine Intestinal Epithelial Cell Permeability
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显著的亚细胞局部化和表皮细胞长髓轻链激酶拼接变体的调节背后的机制

Sandra D Chanez-Paredes1, Shabnam Abtahi1, Juanmin Zha2

  • 1Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

The Journal of biological chemistry
|January 10, 2024
PubMed
概括

菌素轻链激酶 (MLCK) 变体MLCK1和MLCK2在肠上皮质屏障功能中起着不同的作用. 在MLCK1中,特定的域对其周节局部定位至关重要,为炎症性肠病提供治疗点.

关键词:
这就是Actin Actin.障碍物功能障碍 障碍物功能障碍炎症性肠病 (IBD) 是一种炎症性肠病.肠道上皮质 肠道上皮质肠道的通透性 肠道的通透性肌酸氨酸轻链激酶酶的作用紧密的交叉路口紧密的连接瘤亡因子 (TNF) 是一种因子.

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