冠状病毒和脏:一个更新
Samira Bell1, Griffith B Perkins2, Urmila Anandh3
1Division of Population Health and Genomics, University of Dundee, Dundee, Scotland.
Seminars in nephrology
|January 10, 2024
概括
新型冠状病毒病2019 (COVID-19) 严重影响脏健康,特别是在慢性脏病 (CKD) 和移植接受者中. 这篇评论详细介绍了COVID-19的细节.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 由SARS-CoV-2引起的2019年冠状病毒病 (COVID-19) 已经造成了具有持久健康后果的全球大流行.
- 免疫功能低下的个体,包括移植患者和透析患者,面临着较差的结果,免疫反应受损和长期感染.
- 慢性病 (CKD) 增加了对COVID-19的易感性,住院风险和死亡率.
研究的目的:
- 审查目前关于COVID-19对脏健康影响的证据.
- 检查对慢性病患者的影响,包括对置换疗法患者的影响.
- 讨论COVID-19相关的急性损伤 (AKI).
主要方法:
- 这项研究是对现有科学文献和证据的审查.
- 它综合了COVID-19对功能和患者结果的影响的数据.
- 该审查涵盖了对CKD患者和COVID-19相关AKI的影响.
主要成果:
- 通过直接和间接的机制,COVID-19可以导致急性损伤 (AKI).
- 虽然COVID-19 AKI的发病率正在下降,但它仍然与不良结果有关.
- 长期影响包括感染后几个月功能持续下降.
结论:
- COVID-19对脏健康构成重大风险,特别是对于已经存在CKD的人来说.
- 该病毒可以导致急性和慢性损伤.
- 需要继续进行研究,以了解和减轻COVID-19的长期脏后果.
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