一个健康的参与者实验室模型的外周热过热的评估:一个生理学研究
G Chang1, H Moiteiro Manteigas2, P H Strutton1
1MSk Lab, Imperial College London, London, UK.
International journal of obstetric anesthesia
|January 10, 2024
概括
在分娩期间的外周止痛可能会通过限制热量损失而导致孕产妇的高温症. 这项研究模拟了这种效应,发现隔热显著减少了散热,可能导致危险的温度升高.
科学领域:
- 身体生理学 身体生理学
- 麻醉学 麻醉学
- 热调节 热调节 热调节
背景情况:
- 在21%的病例中,产后外周止痛与母亲的高温有关,其机制尚不清楚.
- 一种拟议的机制涉及胆固醇交感神经的阻塞,损害血管扩张和出汗,从而限制热损失.
- 在分娩期间增加的热量产生,加上减少的热量损失,可能导致母亲的体温升高.
研究的目的:
- 为了测试一种新的实验室模型,模拟外围注射器相关的高温症.
- 为了研究减少热损失对核心体温的影响.
- 使用运动来模仿与劳动相关的热量产生和表面绝缘,以模拟外周术效应.
主要方法:
- 十二名健康的参与者在人体表上以20瓦的功率进行了为期两小时的自行车运动.
- 该研究比较了带有和没有表面绝缘的条件 (模拟外周止痛).
- 核心和皮肤温度,热量损失,平均体温和热量产生被连续监测和计算.
主要成果:
- 运动在绝缘 (干预) 和无绝缘 (控制) 条件下同样增加了热量产生.
- 与对照组相比,干预组的总热量损失显著减少 (115W对129W).
- 两组的平均体温都增加了,但与绝缘 (0.47°C对比0.25°C) 的上升明显更大.
结论:
- 实验室模型表明,产后外周止痛可以将热损失限制在14瓦以上.
- 这种经过验证的模型可能有助于评估预防和治疗外围注射器相关的孕产妇高温症的干预措施.
- 需要进一步的研究来验证这种模型在临床环境中.
相关概念视频
01:14Assessing Body Temperature - Oral
Here are the steps to accurately measure oral temperature using an electronic thermometer:
Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
Instruct the patient to open their mouth and place...
Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
Instruct the patient to open their mouth and place...
01:27Assessing Body Temperature - Rectal
Rectal temperature measurement is considered the most precise method for assessing core body temperature and typically registers higher than oral temperature. For adults, the rectal thermometer should be inserted 1 to 1.5 inches into the rectum to obtain the most accurate reading.
Follow these steps for rectal temperature assessment:
Step 1: Perform hand hygiene and don clean gloves to prevent cross-infection.
Step 2: Position the patient in a side-lying position to better visualize the rectal...
Follow these steps for rectal temperature assessment:
Step 1: Perform hand hygiene and don clean gloves to prevent cross-infection.
Step 2: Position the patient in a side-lying position to better visualize the rectal...
01:14Assessing Body Temperature - Axilla
Procedural Guide for Assessing Axillary Body Temperature using a Digital Thermometer:
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
01:19Assessing Body Temperature - Temporal Artery
Here is a stepwise guide to assessing the body temperature at the temporal artery using a temporal artery thermometer
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's forehead...
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's forehead...