关于在日本将传染病疫苗纳入常规疫苗接种的问题,以及加快疫苗接种进程的考虑
Atsuko Okumoto1, Yumiko Nomura1, Shin Okuda1
1Graduate School of Pharmaceutical Sciences, Tokyo University of Science, 162-8601 Tokyo, Japan.
Vaccine
|January 10, 2024
概括
在日本,将批准的疫苗引入常规计划需要太长的时间. 加快疫苗引入需要改进的流行病学数据收集系统,以平衡临床试验结果与现实世界疾病负担和安全信息.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 卫生政策 卫生政策
背景情况:
- 常规接种疫苗对于预防传染病至关重要.
- 在日本,疫苗批准和整合到常规计划之间存在显著的延迟,可能超过10年.
研究的目的:
- 调查将批准疫苗引入常规计划中的信息要求.
- 为了确定日本时间延长的原因.
- 提出促进疫苗及时整合的方法.
主要方法:
- 分析了日本卫生科学理事会免疫和疫苗委员会公布的数据.
- 确定关键讨论点:疾病负担,有效性,安全性和成本效益.
主要成果:
- 目前的评估很大程度上依赖于流行病学数据,收集这些数据可能很慢,特别是对于罕见的不良反应和需要强剂量的情况.
- 延迟决策可能会导致传染病传播的风险.
- 临床试验数据提供了更快的评估,但缺乏长期的流行病学见解.
结论:
- 疫苗的引入可能需要利用临床试验数据来更快地做出决定.
- 迫切需要一个强大的流行病学信息收集系统来评估疾病负担,不良反应和增强剂需求.
- 简化数据收集可以加速疫苗整合,提高公共卫生保护.
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