10毫米直径气球的最佳扩张持续时间在有限的内镜缩术后用于常见的胆道结石:一项随机对照试验
Yuan-Yuan Li1, Yin-Shui Miao1, Cai-Feng Wang1
1Department of Gastroenterology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Scientific reports
|January 10, 2024
概括
在有限的内镜缩切除术 (EST) 后,为期3分钟的气球扩张对于常见的胆道结石去除是最佳的. 这种持续时间降低了ERCP后胰腺炎的风险,而不是1分钟的扩张.
科学领域:
- 胃肠病学 胃肠病学
- 内镜逆行胆血管细胞造影 (ERCP) 是一种内镜逆行胆血管细胞造影.
- 胆道疾病 胆道疾病
背景情况:
- 限定的内镜缩切除术 (EST) 与内镜乳头气球扩张 (EPBD) 结合,是胆固醇胆症的常见治疗方法.
- 在此过程中,气球扩张的最佳持续时间尚未确定.
研究的目的:
- 为了确定10毫米直径气球扩张的最佳持续时间,在有限的EST后,在患有胆固醇胆病的患者中.
主要方法:
- 一项随机对照试验,涉及320名接受深胆道管治疗的患者.
- 患者被分配接受10毫米气球扩张,时间为1分钟 (n=160) 或3分钟 (n=160).
- 石头提取的成功率和ERCP后胰腺炎 (PEP) 的发病率在各组之间进行了比较.
主要成果:
- 在1分钟和3分钟扩张组之间没有观察到石头提取成功率的显著差异.
- 在1分钟组 (10.6%) 中,PEP的发生率明显高于3分钟组 (4.4%) (P=0.034).
- PEP的独立风险因素包括导线进入胰腺管道,管时间>5分钟,气球扩张1分钟.
结论:
- 在有限的EST后,为10毫米气球扩张3分钟的持续时间是常见胆道结石去除的最佳方法.
- 扩张时间较长 (3分钟) 与ERCP后胰腺炎的发病率较低有关.
- 这一发现为优化胆固醇胆病的ERCP程序提供了关键指导.
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