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Updated: Jul 6, 2025

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
11:37

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

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受到2'-O-二硫化物桥梁约束的RNA的合成和特性

Diallo Traoré1, Elisa Biecher1, Manon Mallet1

  • 1CNRS, ENSCM, 1919 route de Mende, 34293, Montpellier Cedex 5, France.

ChemistryOpen
|January 11, 2024
PubMed
概括

在RNA发针中的二硫化物 (S-S) 桥梁会影响它们的结构. 较长的桥梁,如二乙烯 (DEE) 和二烯 (DPE) 破坏双重体的稳定性,但保持发针形状,可以控制RNA相互作用.

关键词:
2-OH 修饰的修饰方法有约束的核酸.双硫化物桥梁是什么意思类核酸 (Oligoribonucleotides) 是一种类核酸.胺酸酸盐的含量是多少

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