医院住院患者感染-一项回顾性流行病学研究
Frederico Fonseca1, Mario Forrester2,3,4, Ana Margarida Advinha5,6
1Pharmaceutical Services, Hospital do Espírito Santo, 7000-811 Évora, Portugal.
Healthcare (Basel, Switzerland)
|January 11, 2024
概括
克洛斯特里迪奥伊德困难感染 (CDI) 发生率显著增加,特别是在老年人和医疗保健机构中. 这种增长凸显了对更新预防和治疗策略的迫切需要,以对抗这种严重的感染.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 医疗保健相关的感染
背景情况:
- 艰难杆菌感染 (CDI) 是医院获得和与抗生素相关的腹的主要原因,导致显著的发病率和死亡率.
- 全球CDI的流行病学趋势正在发展,需要更新本地数据.
研究的目的:
- 分析葡萄牙医院住院患者中CDI的流行病学背景,严重程度和结果.
- 将当前的CDI趋势与同一机构的历史数据进行比较.
主要方法:
- 在葡萄牙埃沃拉的圣灵医院 (HESE) 进行了一项单中心,观察和回顾性研究.
- 关于CDI病例的数据是从2018年1月到12月收集的.
- 分析包括发病率,患者人口统计,危险因素,严重程度,复发和死亡率.
主要成果:
- 每年CDI发病率为每10,000名患者中的20.7例.
- 患者的平均年龄为76.4岁,83.3%的人超过65岁.
- 大多数CDI病例是通过医疗保健获得的,与最近使用抗生素有关. 严重发作发生在23.3%的人群中,复发发生在16.7%的人群中.
- 老年患者的死亡率不成比例地高. 与2000年相比,CDI发病率高出10.4倍以上,社区相关病例显著增加.
结论:
- 自2000年以来,CDI发病率急剧增加,社区相关感染的显著增加.
- 老年人特别容易受到伤害,严重程度,复发率和死亡率更高.
- 调查结果强调,迫切需要加强在医疗机构中对CDI的监测和控制措施.
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