胃肠道表现与儿童的严重COVID-19有关
Esra Betul Akkoyun1, Bilal Ashraf2, Natasha Hanners1
1Division of Pediatric Infectious Disease, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
胃肠道症状,如腹痛,可能表明儿童患有严重的COVID-19. 早期识别这些儿科病例对于更好的结果至关重要.
科学领域:
- 儿童传染病 儿童传染病
- 病毒性呼吸道疾病病毒性呼吸道疾病
- 胃肠病学 胃肠病学
背景情况:
- 儿童可能会出现各种各样的COVID-19症状,从轻度到重度.
- 预先存在的医疗条件可以加剧COVID-19在儿科患者的严重程度.
研究的目的:
- 为了确定与儿童严重COVID-19相关的因素.
- 为了比较住院和非住院儿科COVID-19病例的特征.
- 为了区分小儿科COVID-19患者在重症监护病房 (ICU) 的治疗结果与一般病房患者的治疗结果.
主要方法:
- 一个单一中心的病例控制研究,涉及253名被诊断患有COVID-19的儿科患者.
- 基于住院状态 (医院与非医院) 的患者分类.
- 评估重症监护室 (ICU) 的入院情况 (ICU与地板).
主要成果:
- 36%的儿童COVID-19患者至少有一种潜在的疾病,最常见的是肺部疾病 (例如喘).
- 入院儿童更有可能患有阻塞性睡眠呼吸暂停 (OSA) 和神经发育障碍等并发症.
- 胃肠道症状 (腹部疼痛) 和呼吸道症状 (呼吸短促,腹) 在严重病例和ICU入院中更为频繁.
结论:
- 早期识别严重的儿科COVID-19对于改善患者结果至关重要.
- 呈现时的胃肠道症状与儿童更严重的COVID-19疾病有关.
- 潜在的疾病增加了儿科患者严重COVID-19结局的风险.
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