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患者报告的性功能,膀功能和生活质量,对于患有直肠下部癌症的患者,有或没有永久性骨髓修复
Michael K Rooney1, Melisa Pasli1, George J Chang2
1Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
患有低直肠癌的患者经历了腹腔切除 (APR) 和永久性骨髓切除,报告生活质量 (QOL) 较低. 术对性和泌尿功能产生负面影响,以及影响社会福祉的胃肠道挑战.
科学领域:
- 在瘤学瘤学.
- 外科手术的结果
- 生活质量研究 研究 生命质量研究
背景情况:
- 低的直肠癌往往需要腹腔切除 (APR),导致永久性骨,尽管有器官保护方面的进步.
- 了解骨术对长期生活质量 (QOL) 的影响对于患者护理至关重要.
研究的目的:
- 在患有低直肠癌的个人中,描述患者报告的QOL,包括性和膀功能.
- 为了比较患有和没有永久性骨髓损伤的患者之间的QOL结果.
主要方法:
- 对患者进行了包括FACT-G7,ICIQ MLUTS/FLUTS和IIEF-5/FSFI在内的综合调查.
- 描述性统计和单变量比较分析了人口统计,治疗和QOL分数.
主要成果:
- 患有骨髓切割的患者报告总体QOL数量较低 (FACT-G7) 和性功能更差.
- 尿功能指标 (MLUTS/FLUTS) 在瘤患者中明显恶化 (p=0.01).
- 造骨术患者报告胃肠道问题影响社会活动和人际关系.
结论:
- 在低直肠癌治疗后的永久性静脉切除术可能对患者的QOL产生多维负面影响.
- 这些发现凸显了进一步前性调查的必要性,并可以为有关器官保存与口腔切除的共同决策提供信息.
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