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胰腺囊大小测量磁共振成像与病理学相比

Daniel Jeong^1,2, Brian Morse¹, Stuart Lane Polk³

¹Department of Diagnostic Imaging and Interventional Radiology, H. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, USA.

|January 11, 2024

概括

磁共振成像 (MRI) 准确地测量了胰腺内导管内皮质粘膜瘤 (IPMN) 的大小,尽管它可能略高估计了与病理学相比的长度. 这一发现有助于通过MRI测量来完善IPMN治疗策略.

科学领域:

胃肠病学胃肠病学
放射学放射学是一门学科.
在瘤学瘤学.

背景情况:

胰腺导管内 papillary 粘膜性瘤 (IPMN) 需要准确的尺寸评估来做出治疗决定.
目前的磁共振成像 (MRI) 序列缺乏最佳IPMN尺寸测量的普遍标准化.
建议使用T2加权序列,但它们与病理大小的相关性需要进一步研究.

研究的目的:

为了比较IPMN长轴测量在7个常见的MRI序列与术后病理的协议和偏差.
评估MRI衍生IPMN大小与实际病理大小之间的相关性.
评估MRI测量对观察者之间的协议.

主要方法:

对手术切除的IPMN病例与手术前MRI的回顾性分析.
在七个MRI序列上测量IPMN长轴直径.
使用一致性相关系数 (CCC) 和布兰德-阿尔特曼分析对MRI测量与病理学的比较.
使用类内相关系数 (ICC) 评估观察者间的协议.

主要成果:

最大MRIIPMN大小显示与病理学有很强的一致性 (CCC = 0.82).
在轴向T1动脉后对比和MRCP冠状系列中经常观察到最大尺寸.
核磁共振成像测量倾向于高估IPMN大小与病理相比 (偏差+0.34厘米),可能是由于甲固定.
放射科医生观察者之间的一致性很高 (ICCs 0.740.91).

结论:

通过MRI确定的IPMN最大大小与病理大小有很强的相关性.
磁力共振成像测量可能会高估IPMN长度,可能是由于组织加工工件造成的.
这些发现支持使用MRI进行IPMN大小评估,同时承认潜在的高估.

关键词:

导管内 papillary 粘膜性瘤的发生.磁共振成像技术的使用尺寸测量尺寸测量尺寸测量方法

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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...