尼古丁胺作为NMSCs中的化疗预防剂的作用:系统性审查和元分析
Giulio Tosti1, Francesca Pepe1, Patrizia Gnagnarella2
1Dermato-Oncology Unit, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Nutrients
|January 11, 2024
概括
口服尼古丁胺 (维生素B3) 在高风险患者中没有显著降低非黑色素瘤皮肤癌 (NMSC) 发生率. 虽然通常是安全的,但目前的证据不足以支持其用于NMSC化疗预防的使用.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 营养科学 营养科学
背景情况:
- 尼古丁胺是维生素B3的活性形式,对细胞能量代谢和生存途径至关重要.
- 它已被研究为抗行为性角质炎和非黑色素瘤皮肤癌 (NMSC) 的化学预防剂.
结论:
- 这一元分析表明,没有足够的证据表明,口服尼古丁胺胺疗法在高风险患者中显著减少了角质细胞癌症.
- 可能需要进一步的研究来澄清尼亚在预防皮肤癌症中的作用.
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