维生素D新陈代谢的动态评估在后巴里亚特病患者
Alexandra Povaliaeva1, Artem Zhukov1, Alina Tomilova1
1The National Medical Research Centre for Endocrinology, 117292 Moscow, Russia.
Journal of clinical medicine
|January 11, 2024
概括
腹腔外科手术患者通常缺乏维生素D,并且矿物质代谢发生变化. 补充剂可能无法完全纠正水平,需要改善监测和患者教育.
科学领域:
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
- 营养科学 营养科学
背景情况:
- 肥胖与和维生素D代谢的改变有关.
- 腹腔外科手术对维生素D代谢的影响仍在争论中.
- 现有的数据缺乏对这些代谢变化的全面了解.
研究的目的:
- 在减肥手术前后对患者的维生素D和矿物代谢进行全面评估.
- 为了将接受手术的肥胖患者的代谢概况与健康对照进行比较.
- 为了评估高剂量胆醇补充剂在手术后的疗效.
主要方法:
- 测量了维生素D代谢物,结合蛋白 (DBP),自由25(OH) D,FGF-23,PTH,,白蛋白,,肌素和的血清水平.
- 30名减肥手术候选人与30名健康志愿者进行了比较.
- 手术后6个月的患者进行了随访,并进行了反复的实验室评估和补充.
主要成果:
- 在手术前,患者表现出高维生素D缺乏,较低的活性1,25(OH) 2D3,和,但与对照组相比,PTH水平相似.
- 在手术组中,DBP水平明显高于手术组.
- 尽管服用高剂量的补充剂,但手术后的25(OH) D3水平仍然低于最佳水平;然而,1,25(OH) 2D3在没有PTH或变化的情况下增加.
结论:
- 腹腔外科手术患者表现出复杂的维生素D和矿物质代谢障碍.
- 目前的补充方案可能不足,突出需要改进的临床指南.
- 密切的患者监测和教育对于管理腹腔外科手术后的代谢健康至关重要.
关键词:
减肥手术 减肥手术是什么质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖维生素D是维生素D的重要组成部分.维生素D缺乏症 维生素D缺乏症更多相关视频
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