甲状腺功能障碍症和甲状腺癌的关联:洞察病变发生和诊断挑战 - - 叙述性综述
Gregorio Scerrino1, Nunzia Cinzia Paladino2, Giuseppina Orlando3
1Unit of Endocrine Surgery, Department of Surgical Oncology and Oral Sciences, University of Palermo, 90127 Palermo, Italy.
Journal of clinical medicine
|January 11, 2024
概括
甲状腺功能障碍症 (HPT) 与甲状腺癌 (TC) 有关,特别是乳头甲状腺癌. 下侧甲状腺激素 (PTH) 可能表明风险,强调需要综合患者评估和管理策略.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 甲状腺功能障碍症 (HPT) 和甲状腺癌 (TC) 分享复杂的关联.
- 初级甲状腺功能障碍症 (PHPT) 经常与甲状腺结节和癌症一起观察到.
研究的目的:
- 系统地审查HPT和TC之间的关系.
- 探索病原遗传机制,临床影响,并发性HPT和TC的管理策略.
主要方法:
- 系统的文献搜索 (2013-2023年) 使用MeSH术语"甲状腺过敏症"和"甲状腺癌".
- 分析了来自PubMed,Web of Science和Scopus数据库的15篇精选文章.
主要成果:
- 证实了PHPT与甲状腺结节/癌症 (2.8%-47.1%) 之间的显著关联.
- 乳头甲状腺癌 (PTC) 在这种关联中表现出偏好,观察到性别差异.
- 在PHPT患者中,较低的术前副甲状腺激素 (PTH) 水平被确定为甲状腺癌的潜在风险因素.
结论:
- 由于HPT和TC的共存,需要对患者进行全面的评估.
- 目前关于管理并发性HPT和甲状腺疾病的指导方针很少,这表明需要进一步研究.
- 阐明潜在机制和完善治疗干预措施对于改善临床管理至关重要.
关键词:
在PTH水平上.甲状腺功能障碍症的高甲状腺功能障碍.副甲状腺切除术 (parathyroidectomy) 是一种切除甲状腺的方法.甲状腺癌是甲状腺癌.甲状腺结节 甲状腺结节甲状腺切除术是指甲状腺切除术.更多相关视频
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